Population Pharmacokinetic Modeling of Acetaminophen and Metabolites in Children After Cardiac Surgery With Cardiopulmonary Bypass

Children undergoing cardiac surgery often receive acetaminophen (paracetamol) as part of their postoperative pain treatment. To date, there is no information on the pharmacokinetics (PK) of acetaminophen in this special population, even though differences, as a result of altered hemodynamics and/or...

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Detalles Bibliográficos
Autores principales: Mian, P., Valkenburg, A.J., Allegaert, K., Koch, B.C.P., Breatnach, C.V., Knibbe, C.A.J., Tibboel, D., Krekels, E.H.J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Pediatric Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6590134/
https://www.ncbi.nlm.nih.gov/pubmed/30633373
http://dx.doi.org/10.1002/jcph.1373

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6590134/
https://www.ncbi.nlm.nih.gov/pubmed/30633373
http://dx.doi.org/10.1002/jcph.1373

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