Development of a highly sensitive gas chromatography–mass spectrometry method preceded by solid‐phase microextraction for the analysis of propofol in low‐volume cerebral microdialysate samples

To date, the commonly used intravenous anesthetic propofol has been widely studied, and fundamental pharmacodynamic and pharmacokinetic characteristics of the drug are known. However, propofol has not yet been quantified in vivo in the target organ, the human brain. Here, cerebral microdialysis offe...

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Detalles Bibliográficos
Autores principales: Guntner, Armin Sebastian, Stöcklegger, Simon, Kneidinger, Michael, Illievich, Udo, Buchberger, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Sample Preparation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6590146/
https://www.ncbi.nlm.nih.gov/pubmed/30637930
http://dx.doi.org/10.1002/jssc.201801066

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6590146/
https://www.ncbi.nlm.nih.gov/pubmed/30637930
http://dx.doi.org/10.1002/jssc.201801066

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