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Galectin‐3 exacerbates ox‐LDL‐mediated endothelial injury by inducing inflammation via integrin β1‐RhoA‐JNK signaling activation

Oxidized low‐density lipoprotein (Ox‐LDL)‐induced endothelial cell injury plays a crucial role in the pathogenesis of atherosclerosis (AS). Plasma galectin‐3 (Gal‐3) is elevated inside and drives diverse systemic inflammatory disorders, including cardiovascular diseases. However, the exact role of G...

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Detalles Bibliográficos
Autores principales: Chen, Xiumei, Lin, Jianzhong, Hu, Tingting, Ren, Zhiyun, Li, Linnan, Hameed, Irbaz, Zhang, Xiaoyu, Men, Chen, Guo, Yan, Xu, Di, Zhan, Yiyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6590151/
https://www.ncbi.nlm.nih.gov/pubmed/30536538
http://dx.doi.org/10.1002/jcp.27910