Amber suppression coupled with inducible surface display identifies cells with high recombinant protein productivity

Cell line development (CLD) for biotherapeutics is a time‐ and resource‐intensive process requiring the isolation and screening of large numbers of clones to identify high producers. Novel methods aimed at enhancing cell line screening efficiency using markers predictive of productivity early in the...

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Detalles Bibliográficos
Autores principales: Chakrabarti, Lina, Zhuang, Li, Roy, Gargi, Bowen, Michael A., Dall’Acqua, William F., Hawley‐Nelson, Pam, Marelli, Marcello
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
ARTICLES
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6590230/
https://www.ncbi.nlm.nih.gov/pubmed/30536645
http://dx.doi.org/10.1002/bit.26892

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6590230/
https://www.ncbi.nlm.nih.gov/pubmed/30536645
http://dx.doi.org/10.1002/bit.26892

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