TREM2 triggers microglial density and age‐related neuronal loss

The microglial triggering receptor expressed on myeloid cells 2 (TREM2) signals via the activatory membrane adaptor molecule TYROBP. Genetic variants or mutations of TREM2 or TYROBP have been linked to inflammatory neurodegenerative diseases associated with aging. The typical aging process goes alon...

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Detalles Bibliográficos
Autores principales: Linnartz‐Gerlach, Bettina, Bodea, Liviu‐Gabriel, Klaus, Christine, Ginolhac, Aurélien, Halder, Rashi, Sinkkonen, Lasse, Walter, Jochen, Colonna, Marco, Neumann, Harald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6590266/
https://www.ncbi.nlm.nih.gov/pubmed/30548312
http://dx.doi.org/10.1002/glia.23563

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6590266/
https://www.ncbi.nlm.nih.gov/pubmed/30548312
http://dx.doi.org/10.1002/glia.23563

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