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MUC1 downregulation promotes TNF‐α‐induced necroptosis in human bronchial epithelial cells via regulation of the RIPK1/RIPK3 pathway

MUC1 (mucin 1), a membrane‐tethered mucin glycoprotein, is highly expressed on the surface of respiratory epithelial cells and plays a key role in anti‐inflammatory and antiapoptotic responses against infections. However, little is known about the link between MUC1 and necroptosis in asthma. This st...

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Detalles Bibliográficos
Autores principales: Zhang, Huojun, Ji, Jiani, Liu, Qian, Xu, Shuyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6590293/
https://www.ncbi.nlm.nih.gov/pubmed/30666647
http://dx.doi.org/10.1002/jcp.28148