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Host cell protein LAMP‐2 is the receptor for Trypanosoma cruzi surface molecule gp82 that mediates invasion

Host cell invasion by Trypanosoma cruzi metacyclic trypomastigote (MT) is mediated by MT‐specific surface molecule gp82, which binds to a still unidentified receptor, inducing lysosome spreading and exocytosis required for the parasitophorous vacuole formation. We examined the involvement of the maj...

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Detalles Bibliográficos
Autores principales: Rodrigues, João Paulo Ferreira, Souza Onofre, Thiago, Barbosa, Bruno Couto, Ferreira, Éden Ramalho, Bonfim‐Melo, Alexis, Yoshida, Nobuko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6590364/
https://www.ncbi.nlm.nih.gov/pubmed/30609224
http://dx.doi.org/10.1111/cmi.13003