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Population Pharmacokinetics and Exposure‐Response Analyses for CPX‐351 in Patients With Hematologic Malignancies

CPX‐351, a dual‐drug liposomal encapsulation of cytarabine and daunorubicin at a synergistic ratio, is approved in the United States for adults with newly diagnosed therapy‐related acute myeloid leukemia or acute myeloid leukemia with myelodysplasia‐related changes. Population pharmacokinetics analy...

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Detalles Bibliográficos
Autores principales: Wang, Qi, Banerjee, Kamalika, Vasilinin, Grygoriy, Marier, J.F., Gibbons, Jacqueline A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6590377/
https://www.ncbi.nlm.nih.gov/pubmed/30566230
http://dx.doi.org/10.1002/jcph.1366