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Cancer chromosome breakpoints cluster in gene‐rich genomic regions

Cancer cells are characterized by chromosome abnormalities, of which some, in particular balanced rearrangements, are associated with distinct tumor entities and/or with specific gene rearrangements that represent important steps in the carcinogenic process. However, the vast majority of cytogenetic...

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Detalles Bibliográficos
Autores principales: Mitelman, Felix, Johansson, Bertil, Mertens, Fredrik, Schyman, Tommy, Mandahl, Nils
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6590459/
https://www.ncbi.nlm.nih.gov/pubmed/30479017
http://dx.doi.org/10.1002/gcc.22713