Glioblastoma endothelium drives bevacizumab‐induced infiltrative growth via modulation of PLXDC1

Bevacizumab, a VEGF‐targeting monoclonal antibody, may trigger an infiltrative growth pattern in glioblastoma. We investigated this pattern using both a human specimen and rat models. In the human specimen, a substantial fraction of infiltrating tumor cells were located along perivascular spaces in...

Descripción completa

Detalles Bibliográficos
Autores principales: Falchetti, Maria Laura, D'Alessandris, Quintino Giorgio, Pacioni, Simone, Buccarelli, Mariachiara, Morgante, Liliana, Giannetti, Stefano, Lulli, Valentina, Martini, Maurizio, Larocca, Luigi Maria, Vakana, Eliza, Stancato, Louis, Ricci‐Vitiani, Lucia, Pallini, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2018
Materias:
Molecular Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6590500/
https://www.ncbi.nlm.nih.gov/pubmed/30414187
http://dx.doi.org/10.1002/ijc.31983

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6590500/
https://www.ncbi.nlm.nih.gov/pubmed/30414187
http://dx.doi.org/10.1002/ijc.31983

Ejemplares similares