Ginkgolide B Mediated Alleviation of Inflammatory Cascades and Altered Lipid Metabolism in HUVECs via Targeting PCSK-9 Expression and Functionality

The potential of oxidized-LDL (Ox-LDL) to elicit inflammatory responses in macrophages leading to the atherosclerosis (AS) progression is well known. Since proprotein convertase subtilisin/Kexin-9 (PCSK-9), the posttranslational regulator of LDL-receptor, is associated with elevated LDL in the circu...

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Detalles Bibliográficos
Autores principales: Wang, Gang, Liu, Zhenbin, Li, Menghu, Li, Yu, Alvi, Sahir Sultan, Ansari, Irfan Ahmad, Khan, M. Salman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6590504/
https://www.ncbi.nlm.nih.gov/pubmed/31281844
http://dx.doi.org/10.1155/2019/7284767

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6590504/
https://www.ncbi.nlm.nih.gov/pubmed/31281844
http://dx.doi.org/10.1155/2019/7284767

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