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Betulinic Acid Induces ROS-Dependent Apoptosis and S-Phase Arrest by Inhibiting the NF-κB Pathway in Human Multiple Myeloma

Betulinic acid (BA), as a prospective natural compound, shows outstanding antitumor bioactivities against many solid malignancies. However, its mechanism against multiple myeloma (MM) remains elusive. Herein, for the first time, we studied the antitumor activity of BA against MM both in vivo and in...

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Detalles Bibliográficos
Autores principales: Shen, Min, Hu, Yiqiang, Yang, Yan, Wang, Lanlan, Yang, Xin, Wang, Bo, Huang, Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6590575/
https://www.ncbi.nlm.nih.gov/pubmed/31281581
http://dx.doi.org/10.1155/2019/5083158