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Betulinic Acid Induces ROS-Dependent Apoptosis and S-Phase Arrest by Inhibiting the NF-κB Pathway in Human Multiple Myeloma
Betulinic acid (BA), as a prospective natural compound, shows outstanding antitumor bioactivities against many solid malignancies. However, its mechanism against multiple myeloma (MM) remains elusive. Herein, for the first time, we studied the antitumor activity of BA against MM both in vivo and in...
Autores principales: | Shen, Min, Hu, Yiqiang, Yang, Yan, Wang, Lanlan, Yang, Xin, Wang, Bo, Huang, Mei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6590575/ https://www.ncbi.nlm.nih.gov/pubmed/31281581 http://dx.doi.org/10.1155/2019/5083158 |
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