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Pharmacological interrogation of TrkA-mediated mechanisms in hippocampal-dependent memory consolidation

In the brain, the TrkA receptor for Nerve Growth Factor (NGF) is expressed primarily in the cholinergic system. TrkA/NGF support neuronal health and function, and deficiencies in this axis are associated with progressive cholinergic neuron atrophy and death, and with cognitive deficit in disorders s...

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Detalles Bibliográficos
Autores principales: Josephy-Hernandez, Sylvia, Pirvulescu, Iulia, Maira, Mario, Aboulkassim, Tahar, Wong, Tak Pan, McKinney, R. Anne, Saragovi, H. Uri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6590805/
https://www.ncbi.nlm.nih.gov/pubmed/31233568
http://dx.doi.org/10.1371/journal.pone.0218036