Cargando…
Pharmacological interrogation of TrkA-mediated mechanisms in hippocampal-dependent memory consolidation
In the brain, the TrkA receptor for Nerve Growth Factor (NGF) is expressed primarily in the cholinergic system. TrkA/NGF support neuronal health and function, and deficiencies in this axis are associated with progressive cholinergic neuron atrophy and death, and with cognitive deficit in disorders s...
Autores principales: | Josephy-Hernandez, Sylvia, Pirvulescu, Iulia, Maira, Mario, Aboulkassim, Tahar, Wong, Tak Pan, McKinney, R. Anne, Saragovi, H. Uri |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6590805/ https://www.ncbi.nlm.nih.gov/pubmed/31233568 http://dx.doi.org/10.1371/journal.pone.0218036 |
Ejemplares similares
-
Combinatorial Assembly of Small Molecules into Bivalent Antagonists of TrkC or TrkA Receptors
por: Brahimi, Fouad, et al.
Publicado: (2014) -
Ultrasound delivery of a TrkA agonist confers neuroprotection to Alzheimer-associated pathologies
por: Xhima, Kristiana, et al.
Publicado: (2021) -
TrkA Co-Receptors: The Janus Face of TrkA?
por: Trouvilliez, Sarah, et al.
Publicado: (2023) -
The Paradoxical Signals of Two TrkC Receptor Isoforms Supports a Rationale for Novel Therapeutic Strategies in ALS
por: Brahimi, Fouad, et al.
Publicado: (2016) -
Systems Pharmacology of the NGF Signaling Through p75 and TrkA Receptors
por: Toni, T, et al.
Publicado: (2014)