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Reciprocal signaling and direct physical interactions between fibroblasts and breast cancer cells in a 3D environment

Tumorigenic cells undergo cell aggregation and aggregate coalescence in a 3D Matrigel environment. Here, we expanded this 3D platform to assess the interactions of normal human dermal fibroblasts (NHDFs) and human primary mammary fibroblasts (HPMFs) with breast cancer-derived, tumorigenic cells (MDA...

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Detalles Bibliográficos
Autores principales: Wessels, Deborah J., Pradhan, Nikash, Park, Yang-Nim, Klepitsch, Megan A., Lusche, Daniel F., Daniels, Karla J., Conway, Kayla D., Voss, Edward R., Hegde, Suchaeta V., Conway, Thomas P., Soll, David R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6590889/
https://www.ncbi.nlm.nih.gov/pubmed/31233557
http://dx.doi.org/10.1371/journal.pone.0218854