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Reciprocal signaling and direct physical interactions between fibroblasts and breast cancer cells in a 3D environment
Tumorigenic cells undergo cell aggregation and aggregate coalescence in a 3D Matrigel environment. Here, we expanded this 3D platform to assess the interactions of normal human dermal fibroblasts (NHDFs) and human primary mammary fibroblasts (HPMFs) with breast cancer-derived, tumorigenic cells (MDA...
Autores principales: | Wessels, Deborah J., Pradhan, Nikash, Park, Yang-Nim, Klepitsch, Megan A., Lusche, Daniel F., Daniels, Karla J., Conway, Kayla D., Voss, Edward R., Hegde, Suchaeta V., Conway, Thomas P., Soll, David R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6590889/ https://www.ncbi.nlm.nih.gov/pubmed/31233557 http://dx.doi.org/10.1371/journal.pone.0218854 |
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