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Inhibition of inflammation by minocycline improves heart failure and depression-like behaviour in rats after myocardial infarction

RATIONALE: Patients with heart failure have an increased incidence of depression. Central and peripheral inflammation play a major role in the pathophysiology of both heart failure and depression. AIM: Minocycline is an antibiotic that inhibits microglia activation and release of pro-inflammatory cy...

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Detalles Bibliográficos
Autores principales: Wang, Hong-Wei, Ahmad, Monir, Jadayel, Rami, Najjar, Fatimah, Lagace, Diane, Leenen, Frans H. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6590948/
https://www.ncbi.nlm.nih.gov/pubmed/31233508
http://dx.doi.org/10.1371/journal.pone.0217437