Mouse TRPA1 function and membrane localization are modulated by direct interactions with cholesterol

The cation channel TRPA1 transduces a myriad of noxious chemical stimuli into nociceptor electrical excitation and neuropeptide release, leading to pain and neurogenic inflammation. Despite emergent evidence that TRPA1 is regulated by the membrane environment, it remains unknown whether this channel...

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Detalles Bibliográficos
Autores principales: Startek, Justyna B, Boonen, Brett, López-Requena, Alejandro, Talavera, Ariel, Alpizar, Yeranddy A, Ghosh, Debapriya, Van Ranst, Nele, Nilius, Bernd, Voets, Thomas, Talavera, Karel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Biochemistry and Chemical Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6590989/
https://www.ncbi.nlm.nih.gov/pubmed/31184584
http://dx.doi.org/10.7554/eLife.46084

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6590989/
https://www.ncbi.nlm.nih.gov/pubmed/31184584
http://dx.doi.org/10.7554/eLife.46084

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