Cargando…
Mouse TRPA1 function and membrane localization are modulated by direct interactions with cholesterol
The cation channel TRPA1 transduces a myriad of noxious chemical stimuli into nociceptor electrical excitation and neuropeptide release, leading to pain and neurogenic inflammation. Despite emergent evidence that TRPA1 is regulated by the membrane environment, it remains unknown whether this channel...
Autores principales: | Startek, Justyna B, Boonen, Brett, López-Requena, Alejandro, Talavera, Ariel, Alpizar, Yeranddy A, Ghosh, Debapriya, Van Ranst, Nele, Nilius, Bernd, Voets, Thomas, Talavera, Karel |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6590989/ https://www.ncbi.nlm.nih.gov/pubmed/31184584 http://dx.doi.org/10.7554/eLife.46084 |
Ejemplares similares
-
Differential interactions of bacterial lipopolysaccharides with lipid membranes: implications for TRPA1-mediated chemosensation
por: Startek, Justyna B., et al.
Publicado: (2018) -
The Agonist Action of Alkylphenols on TRPA1 Relates to Their Effects on Membrane Lipid Order: Implications for TRPA1-Mediated Chemosensation
por: Startek, Justyna B., et al.
Publicado: (2021) -
Activation of Drosophila melanogaster TRPA1 Isoforms by Citronellal and Menthol
por: Boonen, Brett, et al.
Publicado: (2021) -
Gustatory-mediated avoidance of bacterial lipopolysaccharides via TRPA1 activation in Drosophila
por: Soldano, Alessia, et al.
Publicado: (2016) -
Expression and Functional Role of TRPV4 in Bone Marrow-Derived CD11c(+) Cells
por: Naert, Robbe, et al.
Publicado: (2019)