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Pro-inflammatory Aorta-Associated Macrophages Are Involved in Embryonic Development of Hematopoietic Stem Cells

Hematopoietic stem cells (HSCs) are generated from specialized endothelial cells of the embryonic aorta. Inflammatory factors are implicated in regulating mouse HSC development, but which cells in the aorta-gonad-mesonephros (AGM) microenvironment produce these factors is unknown. In the adult, macr...

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Detalles Bibliográficos
Autores principales: Mariani, Samanta Antonella, Li, Zhuan, Rice, Siobhan, Krieg, Carsten, Fragkogianni, Stamatina, Robinson, Mark, Vink, Chris Sebastiaan, Pollard, Jeffrey William, Dzierzak, Elaine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591003/
https://www.ncbi.nlm.nih.gov/pubmed/31178352
http://dx.doi.org/10.1016/j.immuni.2019.05.003