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Pro-inflammatory Aorta-Associated Macrophages Are Involved in Embryonic Development of Hematopoietic Stem Cells
Hematopoietic stem cells (HSCs) are generated from specialized endothelial cells of the embryonic aorta. Inflammatory factors are implicated in regulating mouse HSC development, but which cells in the aorta-gonad-mesonephros (AGM) microenvironment produce these factors is unknown. In the adult, macr...
Autores principales: | Mariani, Samanta Antonella, Li, Zhuan, Rice, Siobhan, Krieg, Carsten, Fragkogianni, Stamatina, Robinson, Mark, Vink, Chris Sebastiaan, Pollard, Jeffrey William, Dzierzak, Elaine |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591003/ https://www.ncbi.nlm.nih.gov/pubmed/31178352 http://dx.doi.org/10.1016/j.immuni.2019.05.003 |
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