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Genome plasticity in Candida albicans is driven by long repeat sequences

Genome rearrangements resulting in copy number variation (CNV) and loss of heterozygosity (LOH) are frequently observed during the somatic evolution of cancer and promote rapid adaptation of fungi to novel environments. In the human fungal pathogen Candida albicans, CNV and LOH confer increased viru...

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Detalles Bibliográficos
Autores principales: Todd, Robert T, Wikoff, Tyler D, Forche, Anja, Selmecki, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591007/
https://www.ncbi.nlm.nih.gov/pubmed/31172944
http://dx.doi.org/10.7554/eLife.45954