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Genome plasticity in Candida albicans is driven by long repeat sequences
Genome rearrangements resulting in copy number variation (CNV) and loss of heterozygosity (LOH) are frequently observed during the somatic evolution of cancer and promote rapid adaptation of fungi to novel environments. In the human fungal pathogen Candida albicans, CNV and LOH confer increased viru...
Autores principales: | Todd, Robert T, Wikoff, Tyler D, Forche, Anja, Selmecki, Anna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591007/ https://www.ncbi.nlm.nih.gov/pubmed/31172944 http://dx.doi.org/10.7554/eLife.45954 |
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