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Structural Basis of an Asymmetric Condensin ATPase Cycle

The condensin protein complex plays a key role in the structural organization of genomes. How the ATPase activity of its SMC subunits drives large-scale changes in chromosome topology has remained unknown. Here we reconstruct, at near-atomic resolution, the sequence of events that take place during...

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Detalles Bibliográficos
Autores principales: Hassler, Markus, Shaltiel, Indra A., Kschonsak, Marc, Simon, Bernd, Merkel, Fabian, Thärichen, Lena, Bailey, Henry J., Macošek, Jakub, Bravo, Sol, Metz, Jutta, Hennig, Janosch, Haering, Christian H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591010/
https://www.ncbi.nlm.nih.gov/pubmed/31226277
http://dx.doi.org/10.1016/j.molcel.2019.03.037