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Metabolomics-Driven Exploration of the Chemical Drug Space to Predict Combination Antimicrobial Therapies

Alternative to the conventional search for single-target, single-compound treatments, combination therapies can open entirely new opportunities to fight antibiotic resistance. However, combinatorial complexity prohibits experimental testing of drug combinations on a large scale, and methods to ratio...

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Detalles Bibliográficos
Autores principales: Campos, Adrian I., Zampieri, Mattia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591011/
https://www.ncbi.nlm.nih.gov/pubmed/31047795
http://dx.doi.org/10.1016/j.molcel.2019.04.001