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Metabolomics-Driven Exploration of the Chemical Drug Space to Predict Combination Antimicrobial Therapies
Alternative to the conventional search for single-target, single-compound treatments, combination therapies can open entirely new opportunities to fight antibiotic resistance. However, combinatorial complexity prohibits experimental testing of drug combinations on a large scale, and methods to ratio...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Cell Press
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591011/ https://www.ncbi.nlm.nih.gov/pubmed/31047795 http://dx.doi.org/10.1016/j.molcel.2019.04.001 |