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Phosphatidylinositol 5 Phosphate 4-Kinase Regulates Plasma-Membrane PIP(3) Turnover and Insulin Signaling
Phosphatidylinositol 3,4,5-trisphosphate (PIP(3)) generation at the plasma membrane is a key event during activation of receptor tyrosine kinases such as the insulin receptor required for normal growth and metabolism. We report that in Drosophila, phosphatidylinositol 5 phosphate 4-kinase (PIP4K) is...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591132/ https://www.ncbi.nlm.nih.gov/pubmed/31091438 http://dx.doi.org/10.1016/j.celrep.2019.04.084 |