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Phosphatidylinositol 5 Phosphate 4-Kinase Regulates Plasma-Membrane PIP(3) Turnover and Insulin Signaling

Phosphatidylinositol 3,4,5-trisphosphate (PIP(3)) generation at the plasma membrane is a key event during activation of receptor tyrosine kinases such as the insulin receptor required for normal growth and metabolism. We report that in Drosophila, phosphatidylinositol 5 phosphate 4-kinase (PIP4K) is...

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Detalles Bibliográficos
Autores principales: Sharma, Sanjeev, Mathre, Swarna, Ramya, Visvanathan, Shinde, Dhananjay, Raghu, Padinjat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591132/
https://www.ncbi.nlm.nih.gov/pubmed/31091438
http://dx.doi.org/10.1016/j.celrep.2019.04.084