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Propensity of a picornavirus polymerase to slip on potyvirus-derived transcriptional slippage sites
The substitution rates of viral polymerases have been studied extensively. However less is known about the tendency of these enzymes to ‘slip’ during RNA synthesis to produce progeny RNAs with nucleotide insertions or deletions. We recently described the functional utilization of programmed polymera...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591135/ https://www.ncbi.nlm.nih.gov/pubmed/30507373 http://dx.doi.org/10.1099/jgv.0.001189 |