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From stability to dynamics: understanding molecular mechanisms of regulatory T cells through Foxp3 transcriptional dynamics

Studies on regulatory T cells (T(reg)) have focused on thymic T(reg) as a stable lineage of immunosuppressive T cells, the differentiation of which is controlled by the transcription factor forkhead box protein 3 (Foxp3). This lineage perspective, however, may constrain hypotheses regarding the role...

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Detalles Bibliográficos
Autores principales: Bending, D., Ono, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591142/
https://www.ncbi.nlm.nih.gov/pubmed/30076771
http://dx.doi.org/10.1111/cei.13194