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Effects of C-terminal amidation and heptapeptide ring on the biological activities and advanced structure of amurin-9KY, a novel antimicrobial peptide identified from the brown frog, Rana kunyuensis

Rana kunyuensis is a species of brown frog that lives exclusively on Kunyu Mountain, Yantai, China. In the current study, a 279-bp cDNA sequence encoding a novel antimicrobial peptide (AMP), designated as amurin-9KY, was cloned from synthesized double-strand skin cDNA of R. kunyuensis. The amurin-9K...

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Detalles Bibliográficos
Autores principales: Zhang, Fen, Guo, Zhi-Lai, Chen, Yan, Li, Li, Yu, Hai-Ning, Wang, Yi-Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Science Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591156/
https://www.ncbi.nlm.nih.gov/pubmed/30127331
http://dx.doi.org/10.24272/j.issn.2095-8137.2018.070