Selective adrenergic alpha2C receptor antagonist ameliorates acute phencyclidine-induced schizophrenia-like social interaction deficits in rats

RATIONALE: Social withdrawal is a core feature of the negative symptoms of schizophrenia. Currently available pharmacotherapies have only limited efficacy towards the negative symptoms, i.e., there is a significant unmet medical need in the treatment of these symptoms. OBJECTIVE: We wanted to confir...

Descripción completa

Detalles Bibliográficos
Autores principales: Savolainen, Katja, Ihalainen, Jouni, Jalkanen, Aaro J., Forsberg, Markus M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Original Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591184/
https://www.ncbi.nlm.nih.gov/pubmed/30535904
http://dx.doi.org/10.1007/s00213-018-5130-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591184/
https://www.ncbi.nlm.nih.gov/pubmed/30535904
http://dx.doi.org/10.1007/s00213-018-5130-2

Ejemplares similares