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Selective adrenergic alpha2C receptor antagonist ameliorates acute phencyclidine-induced schizophrenia-like social interaction deficits in rats

RATIONALE: Social withdrawal is a core feature of the negative symptoms of schizophrenia. Currently available pharmacotherapies have only limited efficacy towards the negative symptoms, i.e., there is a significant unmet medical need in the treatment of these symptoms. OBJECTIVE: We wanted to confir...

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Detalles Bibliográficos
Autores principales:	Savolainen, Katja, Ihalainen, Jouni, Jalkanen, Aaro J., Forsberg, Markus M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2018
Materias:	Original Investigation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591184/ https://www.ncbi.nlm.nih.gov/pubmed/30535904 http://dx.doi.org/10.1007/s00213-018-5130-2

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