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Activation of somatodendritic 5-HT(1A) autoreceptors reduces the acquisition and expression of cued fear in the rat fear-potentiated startle test

RATIONALE: Fear conditioning is an important factor in the etiology of anxiety disorders. Previous studies have demonstrated a role for serotonin (5-HT)(1A) receptors in fear conditioning. However, the relative contribution of somatodendritic 5-HT(1A) autoreceptors and post-synaptic 5-HT(1A) heteror...

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Detalles Bibliográficos
Autores principales: Zhao, Yulong, Bijlsma, Elisabeth Y., ter Heegde, Freija, Verdouw, Monika P., Garssen, J., Newman-Tancredi, Adrian, Groenink, Lucianne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591185/
https://www.ncbi.nlm.nih.gov/pubmed/30539269
http://dx.doi.org/10.1007/s00213-018-5124-0