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Fucosyltransferase 4 and 7 mediates adhesion of non-small cell lung cancer cells to brain-derived endothelial cells and results in modification of the blood–brain-barrier: in vitro investigation of CD15 and CD15s in lung-to-brain metastasis

PURPOSE: Metastatic non-small cell lung (NSCLC) cancer represents one of the most common types of brain metastasis. The mechanisms involved in how circulating cancer cells transmigrate into brain parenchyma are not fully understood. The aim of this work was to investigate the role of fucosylated car...

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Detalles Bibliográficos
Autores principales: Jassam, Samah A., Maherally, Zaynah, Ashkan, Keyoumars, Pilkington, Geoffrey J., Fillmore, Helen L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591197/
https://www.ncbi.nlm.nih.gov/pubmed/31104223
http://dx.doi.org/10.1007/s11060-019-03188-x