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CDK inhibitors reduce cell proliferation and reverse hypoxia-induced metastasis of neuroblastoma tumours in a chick embryo model

Neuroblastoma is a paediatric cancer with a poor prognosis. This is in part due to widespread metastasis at time of presentation, which is refractory to current treatment modalities. New therapeutic agents that can control not only tumour growth but also metastasis are urgently needed. The different...

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Detalles Bibliográficos
Autores principales: Swadi, Rasha R., Sampat, Keerthika, Herrmann, Anne, Losty, Paul D., See, Violaine, Moss, Diana J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591221/
https://www.ncbi.nlm.nih.gov/pubmed/31235824
http://dx.doi.org/10.1038/s41598-019-45571-8