Phosphatidic acid homeostasis regulated by a type-2 phosphatidic acid phosphatase represents a novel druggable target in malaria intervention

Type-2 phosphatidic acid phosphatase (PAP2) a member of PAP2 superfamily mediates the conversion of phosphatidic acid (PA) to diacylglycerol (DAG) and thus plays a pivotal role in numerous cellular signaling processes in diverse organisms. An elevated level of intracellular PA is detrimental for the...

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Detalles Bibliográficos
Autores principales: Kumar Sah, Raj, Garg, Swati, Dangi, Poonam, Ponnusamy, Kalaiarasan, Singh, Shailja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591222/
https://www.ncbi.nlm.nih.gov/pubmed/31263575
http://dx.doi.org/10.1038/s41420-019-0187-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591222/
https://www.ncbi.nlm.nih.gov/pubmed/31263575
http://dx.doi.org/10.1038/s41420-019-0187-1

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