Augmentation of spinal cord glutamatergic synaptic currents in zebrafish primary motoneurons expressing mutant human TARDBP (TDP-43)

Though there is compelling evidence that de-innervation of neuromuscular junctions (NMJ) occurs early in amyotrophic lateral sclerosis (ALS), defects arising at synapses in the spinal cord remain incompletely understood. To investigate spinal cord synaptic dysfunction, we took advantage of a zebrafi...

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Detalles Bibliográficos
Autores principales: Petel Légaré, Virginie, Harji, Ziyaan A., Rampal, Christian J., Allard-Chamard, Xavier, Rodríguez, Esteban C., Armstrong, Gary A. B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591224/
https://www.ncbi.nlm.nih.gov/pubmed/31235725
http://dx.doi.org/10.1038/s41598-019-45530-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591224/
https://www.ncbi.nlm.nih.gov/pubmed/31235725
http://dx.doi.org/10.1038/s41598-019-45530-3

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