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Augmentation of spinal cord glutamatergic synaptic currents in zebrafish primary motoneurons expressing mutant human TARDBP (TDP-43)
Though there is compelling evidence that de-innervation of neuromuscular junctions (NMJ) occurs early in amyotrophic lateral sclerosis (ALS), defects arising at synapses in the spinal cord remain incompletely understood. To investigate spinal cord synaptic dysfunction, we took advantage of a zebrafi...
Autores principales: | Petel Légaré, Virginie, Harji, Ziyaan A., Rampal, Christian J., Allard-Chamard, Xavier, Rodríguez, Esteban C., Armstrong, Gary A. B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591224/ https://www.ncbi.nlm.nih.gov/pubmed/31235725 http://dx.doi.org/10.1038/s41598-019-45530-3 |
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