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Modeling the Hematopoietic Landscape

Some time ago, we proposed a continuum-like view of the lineages open to hematopoietic stem cells (HSCs); each HSC self-renews or chooses from the spectrum of all end-cell options and can then “merely” differentiate. Having selected a cell lineage, an individual HSC may still “step sideways” to an a...

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Detalles Bibliográficos
Autores principales: Brown, Geoffrey, Ceredig, Rhodri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591273/
https://www.ncbi.nlm.nih.gov/pubmed/31275935
http://dx.doi.org/10.3389/fcell.2019.00104