A novel potent autophagy inhibitor ECDD-S27 targets vacuolar ATPase and inhibits cancer cell survival

Autophagy is a conserved lysosomal-dependent cellular degradation process and its dysregulation has been linked to numerous diseases including neurodegeneration, infectious diseases, and cancer. Modulation of autophagy is therefore considered as an attractive target for disease intervention. We carr...

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Detalles Bibliográficos
Autores principales: Paha, Jiraporn, Kanjanasirirat, Phongthon, Munyoo, Bamroong, Tuchinda, Patoomratana, Suvannang, Naravut, Nantasenamat, Chanin, Boonyarattanakalin, Kanokthip, Kittakoop, Prasat, Srikor, Sirawit, Kongklad, Gunganist, Rangkasenee, Noppawan, Hongeng, Suradej, Utaisincharoen, Pongsak, Borwornpinyo, Suparerk, Ponpuak, Marisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591302/
https://www.ncbi.nlm.nih.gov/pubmed/31235856
http://dx.doi.org/10.1038/s41598-019-45641-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591302/
https://www.ncbi.nlm.nih.gov/pubmed/31235856
http://dx.doi.org/10.1038/s41598-019-45641-x

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