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A novel potent autophagy inhibitor ECDD-S27 targets vacuolar ATPase and inhibits cancer cell survival
Autophagy is a conserved lysosomal-dependent cellular degradation process and its dysregulation has been linked to numerous diseases including neurodegeneration, infectious diseases, and cancer. Modulation of autophagy is therefore considered as an attractive target for disease intervention. We carr...
Autores principales: | Paha, Jiraporn, Kanjanasirirat, Phongthon, Munyoo, Bamroong, Tuchinda, Patoomratana, Suvannang, Naravut, Nantasenamat, Chanin, Boonyarattanakalin, Kanokthip, Kittakoop, Prasat, Srikor, Sirawit, Kongklad, Gunganist, Rangkasenee, Noppawan, Hongeng, Suradej, Utaisincharoen, Pongsak, Borwornpinyo, Suparerk, Ponpuak, Marisa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591302/ https://www.ncbi.nlm.nih.gov/pubmed/31235856 http://dx.doi.org/10.1038/s41598-019-45641-x |
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