Tau is required for the function of extrasynaptic NMDA receptors

Tau is a microtubule-associated neuronal protein found mainly in axons. However, increasing evidence indicates that it is also present in dendrites, where it serves as an essential mediator of synaptic NMDA (N-methyl-D-aspartate) receptor-dependent excitotoxicity. Of note, NMDA receptors can also be...

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Detalles Bibliográficos
Autores principales: Pallas-Bazarra, Noemí, Draffin, Jonathan, Cuadros, Raquel, Antonio Esteban, José, Avila, Jesús
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591308/
https://www.ncbi.nlm.nih.gov/pubmed/31235881
http://dx.doi.org/10.1038/s41598-019-45547-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591308/
https://www.ncbi.nlm.nih.gov/pubmed/31235881
http://dx.doi.org/10.1038/s41598-019-45547-8

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