TICRR Contributes to Tumorigenesis Through Accelerating DNA Replication in Cancers

DNA replication is precisely regulated in cells and its dysregulation can trigger tumorigenesis. Here we identified that the TOPBP1 interacting checkpoint and replication regulator (TICRR) mRNA level was universally and highly expressed in 15 solid cancer types. Depletion of TICRR significantly inhi...

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Detalles Bibliográficos
Autores principales: Yu, Qin, Pu, Shao-Yan, Wu, Huan, Chen, Xiao-Qiong, Jiang, Jian-Jun, Gu, Kang-Shuyun, He, Yong-Han, Kong, Qing-Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591320/
https://www.ncbi.nlm.nih.gov/pubmed/31275851
http://dx.doi.org/10.3389/fonc.2019.00516

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591320/
https://www.ncbi.nlm.nih.gov/pubmed/31275851
http://dx.doi.org/10.3389/fonc.2019.00516

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