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Recombinant production of human α(2)-macroglobulin variants and interaction studies with recombinant G-related α(2)-macroglobulin binding protein and latent transforming growth factor-β(2)

α(2)-Macroglobulins (α(2)Ms) regulate peptidases, hormones and cytokines. Mediated by peptidase cleavage, they transit between native, intact forms and activated, induced forms. α(2)Ms have been studied over decades using authentic material from primary sources, which was limited by sample heterogen...

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Detalles Bibliográficos
Autores principales: Marino-Puertas, Laura, del Amo-Maestro, Laura, Taulés, Marta, Gomis-Rüth, F. Xavier, Goulas, Theodoros
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591361/
https://www.ncbi.nlm.nih.gov/pubmed/31235767
http://dx.doi.org/10.1038/s41598-019-45712-z