Iron-mediated aggregation and toxicity in a novel neuronal cell culture model with inducible alpha-synuclein expression

Parkinson’s disease (PD) represents an increasing problem in society. The oligomerization of alpha-synuclein (αSyn) is a suggested key event in its pathogenesis, yet the pathological modes of action remain to be fully elucidated. To identify potential disease-modifying therapeutics and to study αSyn...

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Detalles Bibliográficos
Autores principales: Bartels, Martin, Weckbecker, Daniel, Kuhn, Peer-Hendrik, Ryazanov, Sergey, Leonov, Andrei, Griesinger, Christian, Lichtenthaler, Stefan F., Bötzel, Kai, Giese, Armin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591385/
https://www.ncbi.nlm.nih.gov/pubmed/31235814
http://dx.doi.org/10.1038/s41598-019-45298-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591385/
https://www.ncbi.nlm.nih.gov/pubmed/31235814
http://dx.doi.org/10.1038/s41598-019-45298-6

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