Multiple Sclerosis patients carry an increased burden of exceedingly rare genetic variants in the inflammasome regulatory genes

The role of rare genetic variation and the innate immune system in the etiology of multiple sclerosis (MS) is being increasingly recognized. Recently, we described several rare variants in the NLRP1 gene, presumably conveying an increased risk for familial MS. In the present study we aimed to assess...

Descripción completa

Detalles Bibliográficos
Autores principales: Vidmar, Lovro, Maver, Ales, Drulović, Jelena, Sepčić, Juraj, Novaković, Ivana, Ristič, Smiljana, Šega, Saša, Peterlin, Borut
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591387/
https://www.ncbi.nlm.nih.gov/pubmed/31235738
http://dx.doi.org/10.1038/s41598-019-45598-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591387/
https://www.ncbi.nlm.nih.gov/pubmed/31235738
http://dx.doi.org/10.1038/s41598-019-45598-x

Ejemplares similares