Functional Roles of Metabolic Intermediates in Regulating the Human Mitochondrial NAD(P)(+)-Dependent Malic Enzyme

Human mitochondrial NAD(P)(+)-dependent malic enzyme (m-NAD(P)-ME) has a dimer of dimers quaternary structure with two independent allosteric sites in each monomer. Here, we reveal the different effects of nucleotide ligands on the quaternary structure regulation and functional role of the human m-N...

Descripción completa

Detalles Bibliográficos
Autores principales: Hsieh, Ju-Yi, Shih, Wan-Ting, Kuo, Yu-Hsuan, Liu, Guang-Yaw, Hung, Hui-Chih
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591397/
https://www.ncbi.nlm.nih.gov/pubmed/31235710
http://dx.doi.org/10.1038/s41598-019-45282-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591397/
https://www.ncbi.nlm.nih.gov/pubmed/31235710
http://dx.doi.org/10.1038/s41598-019-45282-0

Ejemplares similares