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Functional Roles of Metabolic Intermediates in Regulating the Human Mitochondrial NAD(P)(+)-Dependent Malic Enzyme
Human mitochondrial NAD(P)(+)-dependent malic enzyme (m-NAD(P)-ME) has a dimer of dimers quaternary structure with two independent allosteric sites in each monomer. Here, we reveal the different effects of nucleotide ligands on the quaternary structure regulation and functional role of the human m-N...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591397/ https://www.ncbi.nlm.nih.gov/pubmed/31235710 http://dx.doi.org/10.1038/s41598-019-45282-0 |