Durability of cell line xenograft resection models to interrogate tumor micro-environment targeting agents

Angiogenesis is a key tumor microenvironment (TME) event underpinning tumor growth and metastasis. Nevertheless, the relatively poor performance of anti-angiogenic therapies in clinical trials compared to pre-clinical studies implies that classical subcutaneous xenograft models have limited predicti...

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Detalles Bibliográficos
Autores principales: Miller, Ian S., Shiels, Liam P., Conroy, Emer, Connor, Kate, Dicker, Patrick, Gallagher, William M., Donovan, Norma O’, Kerbel, Robert S., Crown, John, Byrne, Annette T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591410/
https://www.ncbi.nlm.nih.gov/pubmed/31235775
http://dx.doi.org/10.1038/s41598-019-45444-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591410/
https://www.ncbi.nlm.nih.gov/pubmed/31235775
http://dx.doi.org/10.1038/s41598-019-45444-0

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